Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that makes it difficult to breathe. It is often caused by long-term exposure to irritating gases or particulate matter, such as those found in tobacco smoke. COPD is characterized by airflow limitation due to inflammation of the airways and destruction of the lung tissue. Symptoms include coughing, wheezing, shortness of breath, and chest tightness. Research in COPD focuses on understanding the underlying mechanisms of the disease, improving diagnostic methods, developing more effective treatments, and identifying strategies for preventing exacerbations and improving quality of life for patients. This research involves studying the impact of environmental factors, genetics, and lifestyle choices on COPD development and progression, as well as exploring new therapeutic approaches, such as bronchodilators, anti-inflammatory medications, and pulmonary rehabilitation programs.